arnoldoj249658/arnoldo1980
1
0
Code Issues Actions Packages Projects Wiki

Add US20060264716A1 - Microneedle with Glucose Sensor And Methods Thereof - Google Patents

Arnoldo Fitz 2025-09-03 18:02:48 +08:00
parent 145622ac28
commit 9336fb9729
1 changed files with 7 additions and 0 deletions
Show Stats Download Patch File Download Diff File Expand all files Collapse all files

7
US20060264716A1 - Microneedle with Glucose Sensor And Methods Thereof - Google Patents.-.md Normal file

@ -0,0 +1,7 @@
<br>Microneedle expertise gives a helpful minimally-invasive methodology to sample blood. On account of their small dimension, microneedles can pierce skin and take minute portions of blood with minimal impact and or pain to the topic. Despite their advantages, [BloodVitals test](https://seeurl.site/nrfangelina20) prior artwork microneedle systems are still somewhat invasive since they involve the extraction of blood from the patient. Implanted in vivo sensors provide another means to pattern blood chemistry that doesn't require blood extraction. It can be desirable to achieve a much less invasive approach that would not extract blood from the affected person and [Blood Vitals](https://trlittlegit.func.tairongkj.com/orvaldeal7743) supply longer measurement instances than in prior art in vivo devices. This invention relates to a microneedle with a glucose sensor. FIG. 3A is a perspective of an array of microneedles with glucose sensors in accordance with embodiments of the current invention. FIG. 4B is a aspect, cross-sectional view of a working microneedle. FIG. 4C is a facet view of one other array of microneedles in accordance with embodiments of the present invention.<br>
<br>10 area of no less than one of the needles which remains uncovered to the conductive substrate and on no less than a portion of the conductive layer. 200 uM tall, 40 uM in diameter on the tip, and far wider at the base. In some embodiments, the needs are no wider at the bottom than the tip or they're solely considerably wider. Microneedles of this measurement have been shown to provide access to interstitial physique fluid with out reaching the capillaries or nerves, so there is no discomfort. This conductive layer is to cowl the needle and its quick base, however not the tip or the encompassing space, so that each needle has an independent electrical connection. These may very well be supplies like glucose oxidase for the detection of glucose level in interstitial fluids followed by a protecting layer to block out frequent interferences. FIG. 1 exhibits an isometric view and FIG. 2 exhibits a section view to show the physical construction and layers.<br>
<br>FIGS. 3A-3B and FIGS. 4A-4C Rows of needles are proven linked collectively in FIGS. 3A-3B and FIGS. 4A-4C , however they could also be individually sensed and inserted. Nafion or [BloodVitals health](https://gitlab-ng.conmet.it/thedagoodisson) PTFE is utilized to block common interferences. This results within the array of needles as shown in FIGS. This background value can be used a baseline from which to measure the analyte of curiosity using the working needles. Having a reference value and dealing values, permits a more sensitive measurement, for the reason that reference value could be subtracted from or divided into the working worth to effectively get rid of body fluid and environmental variations. Therefore, the spirit and scope of the appended claims shouldn't be restricted to the outline of the popular versions contained herein. CROSS REFERENCE TO Related Applications - This utility claims the benefit of U.S. Provisional Application No. 60/674,465 filed Apr. 25, 2005, the entire disclosure of which is incorporated herein by reference. Government SPONSORSHIP - This invention was made with authorities support under Grant NAG3-2744 awarded by NASA.<br>
<br>The federal government has sure rights in the invention. BACKGROUND - Microneedle technology gives a useful minimally-invasive technique to sample blood. Because of their small size, [BloodVitals SPO2](https://projectdiscover.eu/blog/index.php?entryid=19555) microneedles can pierce skin and take minute portions of blood with minimal impression and or ache to the subject. In spite of their advantages, [BloodVitals health](http://42.194.159.64:9981/cecilriley897/3223bloodvitals-test/wiki/What-should-your-Oxygen-Level-be-whenever-you-Sleep%3F) prior art microneedle programs are nonetheless somewhat invasive since they involve the extraction of blood from the patient. Implanted in vivo sensors present another means to sample blood chemistry that does not require blood extraction. Unfortunately, in vivo sensors interact with the physiology and are vulnerable to degradation during use. It would be fascinating to achieve a less invasive strategy that wouldn't extract blood from the patient and provide longer measurement occasions than in prior artwork in vivo devices. Field OF THE INVENTION - This invention relates to a microneedle with a glucose sensor. FIG. 4C is a aspect view of another array of microneedles in accordance with embodiments of the present invention.<br>